What is the impact of cinnamon supplementation on blood pressure? A systematic review and meta-analysis

Ghavami, Abed and Khadem Haghighian, Hossein and Roshanravan, Neda and Ziaei, Rahele and Ghaedi, Ehsan and R Moravejolahkami, Amir and Askari, Gholamreza (2021) What is the impact of cinnamon supplementation on blood pressure? A systematic review and meta-analysis. Endocrine, Metabolic and Immune Disorders - Drug Targets, 21 (5). pp. 956-965.

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Abstract

Aim: This study was designed to make a systematic review and meta-analysis on randomized controlled trials (RCTs) assessing the effect of cinnamon on blood pressure (BP). Methods: A systematic computerized literature search of PubMed, Scopus, Web of Science, Cochrane Library and Google Scholar databases was conducted up to August 2019. All RCTs using cinnamon supplements in adults were included in this systematic review and metaanalysis. Results: Out of 927 records, 8 trials that enrolled 582 participants were included. The pooled effect size showed that SBP did not change following cinnamon supplementation. (WMD: 0.61mmHg; 95% CI: -1.36, 0.14, P= 0.111). Also cinnamon supplementation in long-duration (≥ 8weeks) had a significant effect on SBP (WMD: -1.25 mmHg; 95% CI: -2.22, -0.28, P= 0.012). Pooled analysis showed that cinnamon had a significant effect on DBP (WMD: -0.93mmHg, 95% CI: -1.55 to -0.32, P= 0.003). In addition, results from both duration subsets and high dose (>1500 mg/day) of cinnamon supplementation were significant. Conclusion: Our findings revealed that cinnamon supplementation has favorable effects on DBP although results of SBP were not the same. Nonetheless, further studies are required.

Item Type:	Article
Subjects:	R Medicine > RN Health > RN1005 Health Sciences in Nutrition
Divisions:	University Portal > vice chancellor > vcr
Depositing User:	Mrs Shahrzad Gholami
Date Deposited:	03 Aug 2021 06:24
Last Modified:	03 Aug 2021 06:24
URI:	http://eprints.qums.ac.ir/id/eprint/10929

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