Virulence Factors of Enteric Pathogenic Escherichia coli: A Review

Pakbin, Babak and M. Brück, Wolfram and W. A. Rossen, John (2021) Virulence Factors of Enteric Pathogenic Escherichia coli: A Review. International Journal of Molecular Sciences.

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Abstract: Escherichia coli are remarkably versatile microorganisms and important members of the normal intestinal microbiota of humans and animals. This harmless commensal organism can acquire a mixture of comprehensive mobile genetic elements that contain genes encoding virulence factors, becoming an emerging human pathogen capable of causing a broad spectrum of intestinal and extraintestinal diseases. Nine definite enteric E. coli pathotypes have been well characterized, causing diseases ranging from various gastrointestinal disorders to urinary tract infections. These pathotypes employ many virulence factors and effectors subverting the functions of host cells to mediate their virulence and pathogenesis. This review summarizes new developments in our understanding of diverse virulence factors associated with encoding genes used by different pathotypes of enteric pathogenic E. coli to cause intestinal and extraintestinal diseases in humans. Keywords: enteric pathogenic Escherichia coli; E. coli pathotypes; virulence factor genes

Item Type: Article
Subjects: Q Science > QR Microbiology
Divisions: University Portal > research center > mmrc
Depositing User: mmrc research portal
Date Deposited: 08 Jan 2022 08:46
Last Modified: 08 Jan 2022 08:46
URI: http://eprints.qums.ac.ir/id/eprint/11165

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