Parasites in surgically removed appendices as a neglected public health concern: a systematic review and meta-analysis

Vafae Eslahi, Aida and Olfatifar, Meysam and Houshmand, Elham and Abdoli, Amir and Bijani, Behzad and Hashemipour, Sima and mohammadi, razzagh and Hajialilo, Elham and Abbaszadeh Afshar, Mohammad Javad and mohammadzadeh, alireza and Badri, Milad (2021) Parasites in surgically removed appendices as a neglected public health concern: a systematic review and meta-analysis. Pathogens and Global Health.

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The role of various parasitic infections in the occurrence of appendicitis is illustrated through cases recorded all over the world. The purpose of the current study was to estimate the global prevalence of parasite infestation (other than E. vermicularis) in appendectomy specimens. In the setting of the PRISMA guidelines, multiple databases (Science Direct, Scopus, Web of Science, PubMed, and Google Scholar) were explored in articles published until 28 September 2020. Totally, 62 studies (106 datasets) with 77, 619 participants were included in the analysis. The pooled prevalence of parasites in appendectomy samples was as follows; 0.012% (95% CI; 0.004–0.025) for Ascaris lumbricoides, 0.004% (95% CI; 0.001–0.009) for Trichuris trichiura, 0.025% (95% CI; 0.007–0.052) for Schistosoma mansoni, 0.002% (95% CI; 0.001–0.005) for Taenia spp., 0.061% (95% CI; 0.020–0.122) for Entamoeba histolytica and 0.034% (95% CI; 0.018–0.056) for Giardia lamblia. Our results demonstrated that the risk of appendicitis may increase in the presence of helminth and protozoan infections. As such, the most cases of parasites in appendectomy specimens were reported in developing countries. Regular screening plans for diagnosis, treatment and prevention are needed for prevention of parasitic infection as well as parasitic associated appendicitis, especially in endemic regions of the world. KEYWORDS ,Prevalence; worldwide; appendicitis; parasitic infestation; histopathological methods

Item Type: Article
Subjects: R Medicine > RQ Parasitology
Divisions: University Portal > research center > Metabolic
Depositing User: pr Metabolic diseases research
Date Deposited: 30 Oct 2022 07:37
Last Modified: 30 Oct 2022 07:37
URI: http://eprints.qums.ac.ir/id/eprint/11302

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