qums

Prevalence and characteristics of Restless leg syndrome in children and adolescents with major thalassemia Compared with control group?

mehdizadeh, leila (2016) Prevalence and characteristics of Restless leg syndrome in children and adolescents with major thalassemia Compared with control group? Masters thesis, qazvin university of medical sciences.

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Abstract

Background: Thalassemia is known as the most debilitating chronic and inherited diseases caused by quantitative defective production of hemoglobin.It is necessary to give more attention to sleep and related disorders such as Restless legs syndrome (RLS) to improve quality of life in long-term treatment of thalassemia patients.RLS is an uncomfortable feeling in the legs at night which is aggravated by rest and relieved by movement. Aim: RLS Prevalence and characteristics comparison in patients with major thalassemia with control group. Method:In a case-control study in Ghods hospital at Qazvin province from 2014 to 2015, total of 39 children and adolescent under 18 years old with thalassemia, and 39 healthy matched for age and sex in the control group were included.Standard questionnaire of “International RLS Study Group criteria for the diagnosis of RLS (IRLSG)” was completed. screening questionnaire RLS from a Clinical Guide to Pediatric Sleep,Diagnosisand Management of Sleep problems designed for children and adolescent that completed by their parents. RLS diagnosed with IRLSSGcriteria.Analysis done by correlation test and chi-square with Spss. 16. Significant level was 0.05. Results: RLS prevalence was higher in girls and also in thalassemia patients than control group (36.8% vs. 5.2%).RLS had significant relationship with BMI, caffeine intake and daily performance(p<0.05).there was no significant correlation of RLS with hemoglobin level and ferritin and RLS symptoms in family members. Conclusion: RLS prevalence was higher in thalassemia patients. RLS decreased daily performance and children's school performance. Higher BMI increased the risk of RLS. The results of this study can help to improve the quality of life of patients with thalassemia diagnosis and treatment of restless legs syndrome and control chronic disease. Keywords: Thalassemia Major, Restless legs syndrome, periodic limb movements disorder, probable Restless leg syndrome, definite restless legs syndrome.

Item Type: Thesis (Masters)
Subjects: R Medicine > R Medicine (General)
Divisions: University Thesis > Faculty of Medicine
Depositing User: Medicine School Students
Date Deposited: 21 Jun 2016 04:43
Last Modified: 21 Jun 2016 04:43
URI: http://eprints.qums.ac.ir/id/eprint/3726

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