Correlation between Obstructive Sleep Apnea Syndrome and Cardiac Disease Severity

Javadi, Hamid Reza and Jalilolghadr, Shabnam and Yazdi, Zohreh and RezaieMajd, Zeinab (2014) Correlation between Obstructive Sleep Apnea Syndrome and Cardiac Disease Severity. Hindawi Publishing Corporation Cardiovascular Psychiatry and Neurology. pp. 1-5.

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Abstract

Background. Obstructive sleep apnea (OSA) syndrome is one of the most common respiratory disorders in humans. There is emerging evidence linking OSA to vascular disease, particularly hypertension.The underlying pathophysiological mechanisms that link OSA to cardiovascular diseases such as hypertension, congestive heart failure, and atrial fibrillation are not entirely understood. The aim of this study was to investigate the association of obstructive sleep apnea hypopnea syndrome (OSAHS) with coronary atherosclerotic disease (CAD). Methods. A questionnaire survey based on Berlin questionnaire and Epworth Sleepiness Scale (ESS) was conducted among 406 patients to assess demographic data and the symptoms, such as excessive daytime sleepiness and snoring. Epworth Sleepiness Scale and Berlin questionnaire were completed by all of the patients. Venous blood samples were obtained for biochemical tests. Characteristics of coronary arterieswere collected fromangiographies’ reports. All patientswere divided into two groups based on results from Berlin questionnaire: low risk patients for OSA and high risk patients for OSA. Data were analyzed by SPSS software version 13. Results. Mean age of patientswas 61.8 ± 10.5. 212 (52.2%) patients were categorized as high risk group for apnea. Also, excessive daytime sleepiness was reported in 186 patients (45.8%). The severity of coronary artery involvement, daytime sleepiness, and electrocardiogram abnormalities was significantly higher in high risk patients for OSA compared with low risk patients. High risk patients had higher level of FBS and LDL and lower level of HDL cholesterol (

Item Type:	Article
Subjects:	R Medicine > RC Internal medicine R Medicine > RI Heart
Divisions:	University Portal > research center > Metabolic
Depositing User:	pr Metabolic diseases research
Date Deposited:	09 Jun 2015 08:32
Last Modified:	09 Jun 2015 08:32
URI:	http://eprints.qums.ac.ir/id/eprint/553

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