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Feasible Relation between Glutathione Peroxidase and Febrile Seizure

Mahyar, Abolfazl and Ayazi, Parviz and Dalirani, Reza and Mohammad Hosseini, Behzad and Sarookhani, Mohammad Reza and Javadi, Amir and Esmaeily, Shiva (2016) Feasible Relation between Glutathione Peroxidase and Febrile Seizure. Journal of Neurometabolic Disorder.

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Abstract

Objective We aimed to determine the relationship between serum glutathione peroxidase and febrile seizure. Materials & Methods In this case-control study, 43 children with simple febrile seizure (case group) were compared with 43 febrile children without seizure (control group) in terms of serum glutathione peroxidase level, measured by ELISA method. This study was conducted in Qazvin Children Hospital, Qazvin University of Medical Sciences in Qazvin, Iran in 2012-2013. The results were analyzed and compared in two groups. Results From 43 children 24 (53%) were male and 19 (47%) were female in children with simple febrile seizure, and 26 (60%) were male and 17 (40%) were female in febrile children without seizure (control group) (P=0.827). Serum glutathione peroxidase level was 166 U/ml (SD=107) in the case group and 141 U/ml (SD=90.5) in the control group of no significant difference. Conclusion There was no significant relationship between serum glutathione peroxidase and simple febrile seizure. Thus, it seems that glutathione peroxidase, an essential component of antioxidant system, does not play any role in the pathogenesis of simple febrile seizure.

Item Type: Article
Subjects: R Medicine > R Medicine (General)
Divisions: University Portal > research center > camr
Depositing User: pr Camr research
Date Deposited: 30 May 2018 06:17
Last Modified: 30 May 2018 06:17
URI: http://eprints.qums.ac.ir/id/eprint/7617

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