The comparison effect of dexamethasone and morphine administration (intravenous, intrathecal and local) in pain control following lumbar spinal surgery

Behnamghader, bahareh and Hasani Barzi, Mohsen The comparison effect of dexamethasone and morphine administration (intravenous, intrathecal and local) in pain control following lumbar spinal surgery. Qazvin University Of Medical Science.

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Abstract Background: Patients undergoing lumbosacral surgery experience severe pain after surgery, which increases the incidence and severity of complications, such as prolonged remission periods. The main goal in controlling postoperative pain is to reduce the dose of drugs for more efficacy and fewer complications, while providing proper analgesia. Research methodology: A total of 75 patients suffering from lumbar spine problems requiring more than one segment of lumbar discectomy, laminectomy and fusion surgery were included in the double-blind clinical trial. Patients in need of one-segment surgery as well as trauma , Infection, lumbar tumor, chronic rheumatologic and metabolic diseases such as rheumatoid arthritis, diabetes, liver or kidney failure, malignancies, cardiovascular disease, drug sensitivity to morphine, history of drug dependence, failure to complete cure for treatment, Having previous history of previous lumbar spine surgery, BMI 35, and dissatisfaction Yarmar left the study. At the end of surgery, SeraTill group A was injected with 004.0 mg / kg morphine and 0.1 mg / kg dexamethasone by a surgeon at Dora level. In group B, 004.0 mg / kg of morphine and 0.1 mg / kg dexamethasone by intra-ocular surgery in the surgical area The surgeon was injected. In group C, 0.004 mg / kg of morphine 0.1 mg / kg dexamethasone was injected intradermally before closure of the surgical site. In the three groups, the patients during the hospitalization period were relieved for 5-10 mg intravenous morphine Grams with a minimum interval of 4 hours and maximum daily intake of -60 30 mg depending on the severity of pain Results: The mean of morphine consumption in postoperative days in three groups shows that the morphine consumption after surgery in the systemic group is more than the others, which shows the better effect of intrathecal and topical use in pain control. The mean pain of patients in 6 hours After surgery, 12 hours, 24 and 48 hours were significant. The frequency of nausea in patients at 6, 24, and 48 hours after surgery was significant in the three groups. The nausea symptoms in the long term systemic system may be associated with the patient. The incidence of vomiting among the three groups was significant in the three groups. There are no significant differences between the three groups

Item Type: Article
Subjects: R Medicine > RD Surgery
R Medicine > RP Paramedical > RP102 Anesthesiology
Divisions: University Portal > Hospitals > hosrajaei
Depositing User: Medicine School Students
Date Deposited: 24 Sep 2018 05:23
Last Modified: 24 Sep 2018 05:23
URI: http://eprints.qums.ac.ir/id/eprint/8087

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